What is MVID?

Microvillus Inclusion Disease (MVID) has many names and can be referred to as MID, congenital microvillus atrophy, Davidson’s disease or familial protracted diarrhea. It is a rare life-threatening intestinal disease that affects newborns. The intestine of the affected individual secretes more fluid than it can handle causing a life-threatening amount of diarrhea.

It is mostly found in the Middle East countries such as Turkey and Saudi Arabia. However, it has also been found in the Navajo Nation of the United State of America, with the highest recorded incidence of 1 in 12,000 live births.

MVID is an autosomal recessive disease; this means that the disease is not linked to sex chromosomes and both parents must be carriers of the mutated myosin VB (MYO5B) gene in order for their child to inherit it.

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